Search Results tgf
1.
] regulan pericentrina B y MYH9 en celulas de glioma.
TGF-[beta] and a specific TGF-[beta] inhibitor regulate pericentrin B and MYH9 in glioma cell lines...tumours. The multifunctional cytokine, transforming growth factor-beta (TGF-[beta]), is expressed by grade III/FV gliomas and promotes tumour angiogenesis...
July 1, 2006; Revista Colombiana de Biotecnología
2.
] Activation
ABSTRACT: Transforming growth factor betas (TGF-[beta]s) are multifunctional and pleiotropic...enhancement of extracellular matrix production. TGF-[beta]s are secreted from cells as latent...LAP), and a distinct gene product, latent TGF-[beta] binding protein LTBP. The secreted...
January 1, 2004; Critical Reviews in Clinical Laboratory Sciences
3.
Genzyme Tissue Repair Announces Positive Phase II Data on TGF-beta2 As a Treatment for Diabetic Foot Ulcers.
TGF-beta2 Product Shows Statistically Significant Improvement in Wound Healing CAMBRIDGE, Mass., Aug...successful completion of a phase II clinical trial to evaluate Transforming Growth Factor beta2 (TGF-beta2) as a treatment for diabetic foot ulcers. TGF-beta2 showed statistically significant improvement ...
August 31, 1999; PR Newswire
4.
]1 and high levels of glucose do not increase insulin cell proportions in the avian embryonic pancreas
Abstract TGF-β1 is thought to decrease the proportion...dissimilar way to glucose. Thus, the effect of TGF-β1 on the proportion of β-cells...reduced levels of growth factors including TGF-β1, and a variety of culture media with...
January 1, 2008; In Vitro Cellular & Developmental Biology
5.
Persistence of (TGF-beta1) induction of increased fibroblast contractility
...contraction. Transforming growth factor (TGF)-beta added to such gels can augment contraction...fibrotic phenotype," we hypothesized that TGF-betaexposure may lead to a persistent increase...Eagle medium (DMEM), with or without 100 nM TGF-beta1, TGF-beta2, or TGF-beta3 for 48 h...
March 1, 2001; In Vitro Cellular & Developmental Biology
6.
]1 TYPE II RECEPTOR EXPRESSION IN CULTURED CORTICAL ASTROCYTES
SUMMARY The transforming growth factor-β (TGF-βs) comprise a family of pleiotropic members...serine/threonine kinase receptors, named TGFRI (TGF-β type I receptor) and TGFRII (TGF-β type II receptor). We previously demonstrated...
July 1, 2006; In Vitro Cellular & Developmental Biology
7.
Early Miscues Cause Late Problems, Suggests New Model of Marfan Syndrome; TGF-beta Protein Key to the Genetic Disease.
...activity of an important signaling protein, TGF-beta, likely underlies a variety of problems...mice dramatically improve understanding of TGF-beta's regulation and function and provide...stem from the connective tissue disorder. TGF-beta pulls together what we know clinically...
March 7, 2003; Ascribe Higher Education News Service
8.
]/Activin/Nodal Pathway in Inhibition of Human Embryonic Stem Cell Differentiation by Mechanical Strain
...or undifferentiated cells. We show that TGFβ/Activin/Nodal signaling plays a crucial...strain. Strain-induced transcription of TGFβ1, Activin A, and Nodal, and upregulated...phosphorylation in undifferentiated hESC. TGFβ/Activin/Nodal receptor inhibitor SB431542...
May 15, 2008; Biophysical Journal
9.
Genetic susceptibility in Dupuytren's disease: TGF-(beta)1 polymorphisms and Dupuytren's disease
...genes. Transforming growth factor beta one (TGF-beta1) is a multifunctional cytokine which...matrix. Previous studies have implicated TGF-beta1 in Dupuytren's disease, suggesting...common single nucleotide polymorphisms in TGF-beta1 with the risk of developing Dupuytren...
March 1, 2002; Journal of Bone and Joint Surgery
10.
Genzyme General and Cambridge Antibody Technology To Collaborate on Development of Human Anti-TGF-beta Monoclonal Antibodies.
...human monoclonal antibodies directed against TGF-beta. All clinical indications, with the...worldwide. Other potential applications of anti-TGF-beta treatment include post- surgical scarring...accelerates and substantially strengthens our anti-TGF- beta program, said Henri A. Termeer, chairman...
September 28, 2000; PR Newswire
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