omalizumab (oh- mal -i-zoo-mab) n. a monoclonal antibody administered by subcutaneous injection in the treatment of severe allergic asthma that has not responded to standard therapy. Trade name: Xolaire.

...Response letter from the US Food and Drug Administration (FDA) for their Biologics License Application (BLA) for Xolair(TM) (Omalizumab), which was filed on June 6, 2000. The letter requests additional preclinical and clinical data analyses, as well as pharmacokinetic...

Synopsis Omalizumab is a recombinant humanized monoclonal...asthma in persons 12 years or older. (1) Omalizumab is the first biotechnology drug for...cause bronchospasm. Safety Studies with omalizumab identified two major safety issues...

...Recalcitrant Atopic Dermatitis with Omalizumab. Lane JE, MD, et al. Journal of the...recalcitrant atopic dermatitis treated with omalizumab in an effort to evaluate its efficacy...For all patients, administration of omalizumab occurred every 2 weeks. Treatment duration...

...investigational anti-immunoglobulin-E drug omalizumab experienced about half the number of...open-label study, patients receiving add-on omalizumab had an annualized rate of 4.92 events...206 patients into the trial to receive omalizumab, a compound designed to reduce circulating...

KEYSTONE, COLO. -- Pretreatment with omalizumab to decrease acute systemic reactions...reactions appears to be pretreatment with omalizumab (Xolair), a humanized monoclonal IgE...allergic rhinitis received 9 weeks of omalizumab or placebo followed by 1 day of rush...

...the popular allergic asthma medication omalizumab after months of successful treatment...According to the prescribing information for omalizumab (Xolair), anaphylaxis has occurred within...interview. In theory, anaphylaxis to omalizumab would not occur if the drug were working...

...Asthma, and Immunology. The antibody, omalizumab, probably is effective for urticaria...mast cells has in causing the disorder. Omalizumab is a recombinant, humanized antibody...randomized to treatment with either omalizumab or placebo at Johns Hopkins Medical...

...the popular allergic asthma medication omalizumab after months of successful treatment...According to the prescribing information for omalizumab (Xolair), anaphylaxis has occurred within...medication. In theory, anaphylaxis to omalizumab would not occur if the drug were working...

Keystone, Colo. -- Pretreatment with omalizumab to decrease acute systemic reactions...reactions appears to be pretreatment with omalizumab (Xolair), a humanized monoclonal IgE...allergic rhinitis received 9 weeks of omalizumab or placebo followed by 1 day of rush...