Search Results light chain
1.
Dual Surface Immunoglobulin Light-Chain Expression in B-Cell Lymphoproliferative Disorders
...immunoglohulin heavy chain and a single class of light chain, either κ or λ, are expressed. There...been several reports indicating that double light-chain gene rearrangements or dual light-chain expression can occur in B-cell malignant neoplasms...
June 1, 2006; Archives of Pathology & Laboratory Medicine
2.
Reversible restrictive cardiomyopathy due to light-chain deposition disease
Case Report Systemic light-chain deposition due to plasma cell dyscrasias...the first patient with cardiac light-chain deposition due to multiple myeloma...restrictive cardiomyopathy due to light-chain deposition may be reversible and...
February 1, 2002; Mayo Clinic Proceedings
3.
The V(kappa)III subgroup light chain proteins in AL amyloidosis & autoimmune diseases
Backgroand & objectives: Light chain associated amyloidosis (AL) is...extracellular deposition of immunoglobulin light chain and its fragments. In vitro and...as nodular amorphous aggregates (light chain deposition diseases). These findings...
July 1, 2001; Indian Journal of Medical Research
4.
Lambda II immunoglobulin light chain protein in primary localized rectal amyloidosis
Keywords: Amyloid protein, λ light chain, localized rectal amyloidosis Abbreviations...lambda II; Ig = immunoglobulin; LC=light chain; PVDF=polyvinylidine difluoride; AL=amyloid light chain; AA = amyloid A; SAA = serum amyloid...
December 1, 2007; Amyloid
5.
Elimination of the Need for Urine Studies in the Screening Algorithm for Monoclonal Gammopathies by Using Serum Immunofixation and Free Light Chain Assays
...serum immunofixation and serum free light chain quantitation within 30 days of...serum immunofixation, serum free light chain, urine protein electrophoresis...85.7% had an abnormal serum free light chain κ/λ ratio, 80.8% had...
December 1, 2006; Mayo Clinic Proceedings
6.
Expanding the Pathologic Spectrum of Immunoglobulin Light Chain Proximal Tubulopathy
...symptoms who were found to have light chain restriction limited to proximal...immunofluorescence, 5 patients had light chain restriction in proximal tubular...microscopy, the lysosomal content showed light chain restriction (in 2 cases studied...
September 1, 2007; Archives of Pathology & Laboratory Medicine
7.
A Case of IgM Paraproteinemia in Which Serum Free Light Chain Values Were Within Reference Intervals
...electrophoresis (SPEP) and serum free light chain (FLC) assay as a potential alternative...is used to diagnose and monitor light chain myeloma, primary amyloidosis, and related light chain diseases. Despite the usually quoted...
February 1, 2007; Clinical Chemistry
8.
light chain disease
The Mosby Medical Encyclopedia 10-01-1996 light chain disease, a type of bone marrow cancer in which plasma cell tumors produce only identical light chain proteins. Persons with light chain disease may develop bone lesions in which the...
October 1, 1996; The Mosby Medical Encyclopedia
9.
Quantitative serum free light chain assay in the diagnostic evaluation of AL amyloidosis
...immunohistochemistry; FLC = free light chain; PPV = positive predictive value...with clonal disease of the other light chain subtype. We found that the FLC...hematologic tests to determine light chain clonality and the exclusion other...
December 1, 2005; Amyloid
10.
Mechanical defects of muscle fibers with myosin light chain mutants that cause cardiomyopathy
...including the human myosin ventricular regulatory light chain (vRLC). The effects of four of these mutations...myosin binding protein-C, ventricular essential light chain (vELC), ventricular regulatory light chain (vRLC), troponin I, actin, thin, and troponin...
April 1, 2003; Biophysical Journal
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