Search Results factor xa
1.
Anti-factor Xa monitoring of anticoagulation during cardiopulmonary bypass in a patient with antiphospholipid syndrome
...monitoring both the ACT and anti-factor Xa levels. The cardiopulmonary bypass...bleeding complications. The use of anti-factor Xa levels provided confirmation of adequate...ANTIPHOSPHOLIPID SYNDROME: anticoagulation, anti-factor Xa, cardiopulmonary bypass The antiphospholipid...
February 1, 2003; Anaesthesia and Intensive Care
2.
Tularik Receives Milestone Payment from Eli Lilly and Company; Oral Factor Xa Inhibitor Enters Phase 1 Study for the Treatment of Thrombotic Diseases.
...development of an orally available Factor Xa inhibitor for the prevention and...design and optimize inhibitors of Factor Xa using Tularik's CAMD technology...payment in November 2001 when the Factor Xa compound progressed to an advanced...
November 12, 2002; Business Wire
3.
Schering-Plough and Corvas Expand Research Collaboration to Include Factor Xa.
...commercialization of inhibitors of coagulation Factor Xa, a key enzyme in the blood clotting...The exercise of the option to the Factor Xa program expands the relationship...We believe that our orally active Factor Xa inhibitors will be more effective...
December 16, 1996; Business Wire
4.
Portola Pharmaceuticals Initiates Phase II Trial of Betrixaban, its Novel Oral Factor Xa Inhibitor for Stroke Prevention in Atrial Fibrillation.
...betrixaban, the Company's novel oral Factor Xa inhibitor anticoagulant, for stroke...and dabigatran. Betrixaban inhibits Factor Xa, a validated target for which there...approved drugs on the market. Inhibiting Factor Xa activity appears to offer advantages...
November 3, 2008; PR Newswire
5.
Factor Xa Inhibitors: Future Therapeutic Directions in the Prophylaxis and Treatment of Thrombotic Disorders and Acute Coronary Syndrome
...thrombin) and activated Factor X (Factor Xa).5 Heparins tendency toward AT-independent...inhibiting 2 specific coagulation factors (Factor Xa and thrombin), but with a higher affinity for inhibiting Factor Xa compared with UFH. The introduction...
October 1, 2006; Managed Healthcare Executive
6.
Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis.
...lead compound, PRT054021, an oral Factor Xa inhibitor, today at the XXI Congress...session titled Evaluation of the Factor Xa (fXA) Inhibitor, PRT054021 (PRT021...EXPERT EXPERT (Evaluation of the Factor Xa Inhibitor, PRT054021, against Enoxaparin...
July 10, 2007; PR Newswire
7.
Prophylactic dosing adjustment in pregnancy based upon measurements of anti-factor Xa levels
...necessity for monitoring of anti-factor Xa levels in pregnant women taking low...drug for pregnant patients. Anti-factor Xa activity can be used to monitor concentrations...mean peak concentrations of anti-factor Xa activity when drawn in the first...
November 1, 2005; Journal of Maternal - Fetal & Neonatal Medicine
8.
Portola Pharmaceuticals Licenses Oral Factor Xa Inhibitor, a Potential Chronic Anticoagulant.
...Millennium Pharmaceuticals, Inc.'s Factor Xa inhibitor program. Given orally once...directly on the blood coagulation enzyme Factor Xa, a clinically validated target involved...develop, market and commercialize Factor Xa inhibitors worldwide. Portola will...
August 5, 2004; PR Newswire
9.
Daiichi Sankyo Announces Clinical Study Data for Oral Factor Xa Inhibitor DU-176b.
...showed that the investigational oral Factor Xa inhibitor DU-176b reduced the incidence...forward to further study on this Factor Xa inhibitor, said Gary Raskob, Ph.D...that discovered one of the first Factor Xa small molecules (DX-9065a), we are...
September 2, 2008; PR Newswire
10.
Millennium Initiates Phase I Clinical Trial of MLN1021, A Novel, Oral Factor Xa Inhibitor.
...orally administered inhibitor of Factor Xa, a critical enzyme in the formation...include up to 64 healthy volunteers. Factor Xa is responsible for the conversion...central role in thrombin production. Factor Xa is the catalytic component of this...
December 20, 2002; PR Newswire
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