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1. Cholecystectomy and Acquired Factor VIII Inhibitor Coagulopathy
...with recognized and unrecognized factor VIII inhibitor. The setting was a tertiary...program. Two patients with acquired factor VIII inhibitor coagulopathy required...intravenous immunoglobulin (IVIG) and factor VIII transfusions. An elderly patient...
September 1, 2004; The American Surgeon

2. GenStar Reports Successful Repeated Administration of MAX-AD FACTOR VIII in Pre-Clinical Models at American Society for Hematology Meeting.
...Update Provided on Expression of Factor VIII in First Treated Patient GenStar...In this disease, a defect in the Factor VIII gene results in a decrease in the production of the Factor VIII protein essential for blood clotting...
December 10, 2001; Business Wire

3. Global Factor VIII Supply Shortage Could Ease Following European Committee Positive Opinion; CPMP Issues Positive Opinions for Wyeth's U.S. Recombinant Factor VIII Production Facility and European Recombinant Factor VIII Final Processing Facility.
...Corporation , announced today that its recombinant factor VIII production facilities in St. Louis, Missouri...moroctocog alfa, recombinant coagulation Factor VIII) -- the Company's recombinant factor VIII product for the treatment of hemophilia A...
January 22, 2002; PR Newswire

4. Increased Factor VIII Level as a Risk Factor for DVT.(deep venous thrombosis)
...found that an increased level of factor VIII is associated with venous thrombosis...determine whether an elevated level of factor VIII confers an increased risk of venous...anticoagulant. In addition, the level of factor VIII was checked at this time. Patients...
February 15, 2001; American Family Physician

5. Avigen Reports in Vivo Delivery and Long-Term Expression of Factor VIII Gene For Hemophilia A.
...vector (AAV) carrying the gene for factor VIII produced physiological levels of...animals. Significant levels of factor VIII have persisted in these animals...is the first publication showing factor VIII expression in vivo using AAV. This...
November 1, 1999; PR Newswire

6. The corrupting of Factor VIII. (the hope of hemophiliacs became the deadly agent of AIDS; excerpt from 'And the Band Played On')
THE CORRUPTING OF FACTOR VIII January 1982, Centers for Disease...life expectancy. The invention of Factor VIII--a substance that, when injected...America's 20,000 hemophiliacs. Before Factor VIII, a hemophiliac could expect two, maybe...
March 1, 1988; Saturday Evening Post

7. Bayer HealthCare Reports Positive Preclinical Study Results on Longer-Acting Recombinant Factor VIII Molecules.
PEGylated Forms of Recombinant Factor VIII Show Extended Time of Activity...PEGylated forms of recombinant factor VIII(1) (rFVIII) prolong bleeding protection...native rFVIII. PEGylation Protects Factor VIII from the Inhibition of Antibody...
July 12, 2007; PR Newswire

8. Factor VIII
Factor VIII (antihaemophilic factor) One of the blood clotting factors . Factor VIII is a soluble protein that stimulates the...Haemophilia is due to a deficiency or defect of Factor VIII and is treated by administration of blood...
January 1, 2004; A Dictionary of Biology

9. Georgia Inventor Develops Modified B-domainless Porcine Factor VIII
...and purified B-domainless porcine factor VIII. According to the U.S. Patent...specific amino acid loci of human factor VIII interact with inhibitory antibodies...antibodies after being treated with factor VIII. Modified factor VIII is disclosed...
March 5, 2007; US Fed News Service, Including US State News

10. Baxter Receives Marketing Authorisation From the European Commission for ADVATE to Treat Haemophilia A; -- First Factor VIII Therapy Available in Europe with Innovative Processing to Help Address Safety Concerns --.
...Octocog Alfa Recombinant Coagulation Factor VIII). ADVATE is indicated for the prevention...haemophilia A. It is the first and only factor VIII made without the addition of any...temporarily raising the level of factor VIII in the blood, thus allowing the...
March 3, 2004; PR Newswire