Search Results allele
1.
The Relationship Between Homozygosity and the Frequency of the Most Frequent Allele
...Homozygosity is a commonly used summary of allele-frequency distributions at polymorphic loci. Because high-frequency alleles contribute disproportionately to the...are homozygous for the most frequent allele. To assess the relationship between...
August 1, 2008; Genetics
2.
Evaluation of a New Pooling Strategy Based on Leukocyte Count for Rapid Quantification of Allele Frequencies
Background: Allele frequencies of single-nucleotide polymorphisms...different SNP assays to obtain the exact allele frequencies in the pool. In addition...to generate artificial samples of known allele frequencies. We analyzed pools and mixes...
May 1, 2007; Clinical Chemistry
3.
Simple and Effective Strategies for Detection of Allele Dropout in PCR-Based Diagnosis of Wilson Disease
...described the mechanisms leading to allele dropout in the PCR-based diagnosis of...unequivocal and rapid identification of allele dropout in WD. In WD, an autosomal recessive...variations in the ATP7B gene gives rise to allele dropout, the nonamplification of one of...
August 1, 2006; Clinical Chemistry
4.
High frequency of the Apolipoprotein E asterick4 Allele in African Pygmies and most of the African populations in Sub-Saharan Africa
Abstract Apolipoprotein E genotypes (alleles *2, *3, and *4) have been determined in...unrelated African subSaharan subjects. Allele frequencies for Pygmies are 5.7% for APOE...Mossi; three ethnic groups have a higher allele frequency of APOE*4 (Fon, 29.4%; Zairians...
August 1, 1997; Human Biology
5.
Novel allele found to help leukemia treatment
Novel allele found to help leukemia treatment BEIJING...Chinese scientists have identified a new allele in a girl in southwest China's Sichuan...leukemia treatment. The discovery of the HLA-B allele was made at the HLA (human leukocyte antigen...
January 6, 2004; Xinhua News Agency
6.
Allele Dropout in PCR-Based Diagnosis of Wilson Disease: Mechanisms and Solutions
...We investigated the mechanisms leading to allele dropout-the nonamplification of 1 of the alleles-in PCR-based diagnosis of Wilson disease...blood samples from 6 WD patients (P1-P6) with allele dropouts detected in a previous study of WD...
March 1, 2006; Clinical Chemistry
7.
Directional Positive Selection on an Allele of Arbitrary Dominance
...assume codominance of the beneficial allele. We examine the importance of this...given mean fixation time, a beneficial allele has a much weaker effect on diversity at linked neutral sites when the allele is recessive. THE fixation of a beneficial...
January 1, 2006; Genetics
8.
Company Profile for Allele Biotech.(Company overview)
Allele Biotech (Allele) focuses on innovative research in life sciences. Allele has become a reliable source for superior fluorescent proteins (available for licensing to pharmaceutical companies), highly efficient Luciferase substrates, and genotyping...
September 12, 2008; Business Wire
9.
Allele frequencies of single nucleotide polymorphisms in the second Exon of the myoglobin gene among the Japanese
Abstract The difference in the allele frequencies of two single nucleotide polymorphisms...sequencing. The substitutions were always linked and two alleles were found in the samples used: the A-T allele with no substitution at positions (79A) and (109T...
April 1, 2002; Human Biology
10.
CTG repeat number in the nonaffected allele of myotonic dystrophy patients in not critical for disease expression
...Abstract To investigate whether unusual allele segregation might explain the dominant negative effect of the expanded allele for myotonic dystrophy on myotonin...at the DM locus in the nonaffected alleles of 64 DM (dystrophia myotonia) patients...
December 1, 1997; Human Biology
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